Specifically, interferon alpha and beta (IFNα/β) (Figure 5A, Supplementary Table S8), interferon gamma (IFNγ, Supplementary Table S9) (Figure 5B), and signaling by interleukins (Figure 5E, Supplementary Table S10) were significantly up-regulated in cancer cells isolated from immune-competent mice (SBM). Here, IFNG is linked to cancer.