Likewise, RNA and protein expression levels of Epithelial cell adhesion molecule (EpCAM) and AFP could define prognostically distinct subgroups of HCC, and EpCAM expression was associated with a progenitor gene expression signature, including tyrosine-protein kinase KIT (c-Kit), Wnt activity and CK19 expression [126]. Here, EPCAM is linked to hepatocellular carcinoma.