The following five simple clinical characteristics or laboratory data: large tumor size (≥ 5.6 cm), high WBC count (≥ 5700/μL), low Hb count (≤ 12.4 g/dL), high CRP level (≥ 0.17 mg/dL), and high LDH level (≥ 240 IU/L) can be useful for predicting malignancy of soft tissue tumors. This evidence concerns the gene GSTM1 and neoplasm.