RELA and ependymoma: A DNA methylation profile provided a new ependymoma classification in nine diverse subtypes with different molecular profiles, three per localization in CNS (spinal, posterior fossa, and supratentorial localizations), the group A in posterior fossa, and the REL-associated protein/p65 (RELA) fusion-positive supratentorial ependymomas resulting in worse prognosis, as recently reviewed [1].