A study using immunohistochemistry evaluated the expression of Cellular tumor antigen p53 (P53), Proliferation marker protein Ki-67 (Ki67), cyclin D1, Guanine nucleotide-binding protein G(o) subunit alpha (GNAO1), Acid ceramidase (ASAH1), MICOS complex subunit MIC60 (IMMT), and Importin-7 (IPO7) proteins in ependymal tumors in relation to histopathological grade, age, gender, and progression-free and overall survival, in comparison to control tissue to determine possible prognosis biomarkers [16]. The gene discussed is CCND1; the disease is ependymal tumor.