In OncoBase (http://www.oncobase.biols.ac.cn/), an integrated database for annotating somatic mutations in different cancer types, 289 mutations were described for 3-MST gene in 36 cancers retrieved from The Cancer Genome Atlas (TGCA), although the nature of these mutations with respect to the functionality of 3-MST protein has not yet been elucidated. This evidence concerns the gene MPST and cancer.