IQGAP2 and gastric cancer: Then, to further explore the effect of IQGAP2 knockdown on GC cell migration and invasion, we did wound-healing assays and transwell assays, and found that IQGAP2 knockdown promoted cell migration and invasion in SGC-7901 and MGC-803 similar to the effect of SHIP2 knockdown (Figure 3C,D).