HR and breast cancer: In addition, other ongoing studies with abemaciclib in BC were carried out, such as the neoMONARCH (NCT02441946) phase II clinical trial to compare the biological effects of abemaciclib combination with anastrozole to those of abemaciclib monotherapy and anastrozole monotherapy for two weeks, as well as to evaluate the activity and safety of abemaciclib with anastrozole in a subsequent 14 weeks with HR+/HER2− ABC [150].