POMC and ACTH-producing pituitary gland adenoma: Another gene overexpressed in samples from female patients is EPOR, i.e., the erythropoietin receptor; given that erythropoietin has been shown to modulate ACTH intracellular concentration and secretion in AtT 20 cells [86]; this finding could contribute to the gender-dependent difference ACTH secretion by corticotrope adenoma primary cultures.