Really interesting new gene (RING) finger protein 213 (RNF213) is encoded by the RNF213 gene (DDBJ/EMBL/GenBank accession number AB537889) on chromosome 17q25, which has received considerable attention as a susceptibility gene for MMD and ICASO in Asians [4,5,6]. The gene discussed is RNF213; the disease is multiminicore myopathy.