MPO and myeloid sarcoma: Oxidative stress and mitochondrial metabolism are finely linked in NDDs: myeloperoxidase activity has been shown to be upregulated in the microglia of patients with AD and the brains of patients with MS [87,88], and myeloperoxidase products, namely, hypochlorous acid and chloramine, can inhibit KGDH activity, thus revealing its sensitivity to inflammatory ROS.