APC and cancer: Those with a two-fold change are hsa-miR-92a (logFC −1.08); hsa-miR-19a (logFC −1.06); hsa-miR-17 (logFC −1.05); hsa-miR-135b (logFC −1.4); hsa-miR-20a (logFC −1.07); hsa-miR-20a* (logFC −1.07) and hsa-miR-9* (logFC −1.08), and all are involved in important KEGG pathways such as pathways in cancer, colorectal pathways, bladder cancer and TFG-beta signaling pathway by targeting genes like NRAS, APC, RUNX1, BCL2, MAPK9, CCND1, SMAD4, HIF1A, MYC, CDKN1A, VEGFA, PTEN, TGFBR2, and JAK1 (Tables S9 and S10).