CD8A and neoplasm: We found significantly increased proportions of activated CD69+ CD4+ and CD8+ T cells in the peritumor and tumor (15.25 ± 3.38 and 25.26 ± 4.55 respectively for CD4+ T cells and 14.3 ± 3.74 and 31.87 ± 5.34 respectively for CD8+ T cells), as compared to the PBMC of the same patients and of healthy controls (Figure 4a and Table 5) while the expression intensity was only slightly higher as compared to the PBMC of healthy controls and PBMC of the same patients (Figure 4b and Table 5).