SRSF1 mRNA levels were unaltered upon siRNA or drug inhibition of SRPK1 in HPV-infected keratinocytes (data not shown), suggesting that SRSF1 may undergo proteasomal degradation in the cytoplasm of SRPK1-depleted, or inhibited, non-tumour keratinocytes. This evidence concerns the gene SRSF1 and neoplasm.