CD8A and pancreatic adenocarcinoma: In an investigation carried out by Tahkola K et al., immune scores were an independent prognostic factor for better disease-free survival and overall survival rates in PAAD patients [37], which may owe much to upregulated CD8 T lymphocytes, gamma delta T lymphocytes, resting NK cells, monocytes, and neutrophils in the high immune-score group [37].