NEFL and Huntington disease: It is possible that NfL levels could be indirectly influenced by the modulatory role of lifestyle factors on brain structures, which has been demonstrated in mouse models of HD and cross‐sectional investigations in patients, as well as other neurodegenerative disorders (Bonner‐Jackson et al., 2013; Dellen, Blakemore, Deacon, York, & Hannan, 2000; Trembath et al., 2010).