AKT1 and central nervous system cancer: Progression of the glioma, clinical‐grade diagnosis and prognosis are influenced by PI3K/AKT signalling.28 A loss of control in FGF/FGFR pathways has been associated with the advancement of cancer according to research.19, 29 This oncogenesis is mediated by several target molecules such as PI3K/AKT and others already mentioned above.