The 55 DEGs with |log2 Fold Change| > 2 were marked in the volcano plot, and the relevant heatmap of gene expression in 14 paired cancer and paracancerous samples was shown in Figure 1B. The results showed that the expression level of KRT84 in OSCC tumor samples was significantly lower than that in paracancerous samples. The gene discussed is KRT84; the disease is neoplasm.