A study was done by Smith KJ and Germain M on two known cases of PCOS patients presenting with mucosal pigmentation, suggesting Peutz-Jegher syndrome probably due to the abnormal functioning of serine/threonine-protein kinase 4/liver kinase B1 (STK4/LKB1) protein [8]. Here, STK4 is linked to Peutz-Jeghers syndrome.