In one study, a great number of immune cells were identified, such as interleukin-17 (IL-17), CD45+ leukocytes, CD5+ lymphocytes, γⴃT cells in connection to it and ZNF750/MPZL3 pathway, which plays a critical part in the pathogenesis of SD [23,24]. Additionally, this inflammatory aggregation in SD disrupts the skin barrier called the epidermis and further produces an immune reaction to Malassezia yeasts [25]. The gene discussed is MPZL3; the disease is Salla disease.