Matrix metalloproteinases, particularly MMP‐2 and MMP‐9, are crucial molecules in tumor development, progression, and metastasis (Alaseem et al., 2017; Deryugina & Quigley, 2006; Gong et al., 2016; Lagarrigue et al., 2010; Miao et al., 2017). This evidence concerns the gene MMP2 and neoplasm.