By controlling for multiple testing using FDR, the significant association between LTL and BPF within subgroups of women (p = 0.005), individuals with age >65y (p = 0.006), hypertension (p = 0.004), BMI ≥ 25 (p = 0.009), education ≤ 10y (p = 0.006), CVD (p = 0.010), in non-diabetics (p = 0.003), and Apoe4 non-carriers (0.002) persisted. The gene discussed is APOE; the disease is hypertensive disorder.