The clinical tissue samples of OSCC showed negative correlations between EphrinA3 expression and miR‐210‐3p and E‐cadherin, as well as the pathological grading of tumours.25 Knocking‐down EphrinA3 decreased the expression of E‐cadherin and increased the expression of N‐cadherin and p‐AKT, indicating the activation of the PI3K/AKT signalling pathway. The gene discussed is CDH1; the disease is neoplasm.