EphA receptors usually only bind to ephrinA ligands in a non‐specific manner.9, 10 Moreover, the inhibition of ephrin in turn causes inhibition of ligand‐dependent migration and invasion of tumour cells.11 Our previous research revealed the overexpression of EphA2 and ephrinA1 in OSCC and salivary adenoid cystic carcinoma.12, 13, 14 EphrinA3 plays an important role in the growth and development of the embryonic nervous system, but its role in the occurrence and progression of tumours is unclear. Here, EPHA2 is linked to neoplasm.