The classifier model suggested that the combination of HBB, AMBP, B2M and LYZ may predict more efficiently survival for patients with CKD (p < 0.05) (Fig. 6a) compared to eGFR measurements (p > 0.05), when the cutoff of eGFR was set at 60 mL/min/1.73 m2 (Fig. 6b). This evidence concerns the gene B2M and chronic kidney disease.