Others, such as AML-ETO9a, MLL-AF9, PML-RARα, NRAS G12V, GATA2 R396W, NPM1mut (exon 12 insertion39), and MOZ-TIF2 cooperated with HMGN1 as seen by enhanced myeloid differentiation delay compared to either alteration alone (Fig. 5a, Supplementary Fig. 7a). This evidence concerns the gene KAT6A and acute myeloid leukemia.