We also detected fully traced and highly condensed dermal clusters of cells (resembling dermal condensates) in TD-adjacent infundibula and underneath the regular IFE (Figure 6G, Figure 6—figure supplement 2B), which did not result in de novo HF induction and the dermal cell condensations were entirely negative for SDC1 expression (Figure 6G). The gene discussed is SDC1; the disease is hydrops fetalis.