When comparing day 0 versus 35 post-infection, the top 20 canonical pathways showed a high activation of the immune response through dendritic cell maturation, IL-8 signaling, Leukocyte extravasation signaling, NFAT in regulation of the immune response, P13K signaling in B lymphocytes, Th1 pathway and B cell receptor signaling pathways. The gene discussed is CXCL8; the disease is infection.