Among RNA1–5, RNA1 and RNA2, which are essential for infection and virus replication, encode the housekeeping genes, such as replicase, coat protein, and triple gene block movement protein; the smaller RNAs, RNA3, -4, and -5, are involved in pathogenicity or vector transmission during systemic BNYVV infection of beet or Nicotiana benthamiana [4,5]. This evidence concerns the gene GOLPH3 and infection.