CCR7 and coronary artery disorder: CCR7 has been shown to have a positive role in plaque regression [2,39], likely by facilitating the emigration of macrophages from plaques [40,41], while its genetic depletion was seen to increase T cell accumulation in atherosclerotic lesions and to aggravate ATHp [42], results in agreement with our here reported downregulation of CCR7 expression in CAD patients.