FOXOs have been also linked to the development of ATHp and CAD by inhibiting proliferation and activation of VSMCs and neointimal hyperplasia [50], by mediating protease activated receptor 2 (PAR2)-induced proinflammatory gene expression [51], etc. Lastly, CCR7 and FOXO1 are functionally linked since CCR7 expression is regulated by FOXO1 [52] and both are predicted targets of miR-30a-5p and miR-465a-5p, two of the 13 miRNAs upregulated in ATHp (Table 2). The gene discussed is F2RL1; the disease is coronary artery disorder.