Given the interaction effect, the Lac+TG level was associated with higher OR of HCC in males and females aged between 40 and 80 years, especially in males aged between 60 and 80 years (OR = 15.184, p = 0.001), relative to the OR of LC and CLH in males and females aged between 60 and 80 years. Here, LCT is linked to laryngotracheoesophageal cleft.