Figure 2B shows an average increase in YBX1 protein levels in AURKA-C4-2 cells from three independent experiments. Likewise, AURKA knockdown using corresponding shRNAs decreased YBX1 levels in C-42 cells (Figure 2C,D). Similar results were observed in 22Rv1 cells (Figure 2E–H), suggesting that AURKA positively controls YBX1 in PCa cells. The gene discussed is YBX1; the disease is posterior cortical atrophy.