Figure 4B represents relative protein levels of YBX1 and 2A-YBX1 in C4-2 cells from three independent experiments. Analogous consequences were observed in 22Rv1 cells, indicating the reciprocal cross-talk between YBX1 and AURKA may be a common mechanism in PCa cells (Figure 4C,D and Supplementary Figure S3C). This evidence concerns the gene YBX1 and posterior cortical atrophy.