PKD1 and hyperuricemia: The multivariate analysis that included age, eGFR, PKD1 mutation, urinary protein excretion, hyperuricemia, and serum phosphate showed that eGFR (HR, 0.82; 95% CI, 0.74–0.90; p < 0.001) and serum phosphate (HR, 6.78; 95% CI, 1.94–34.02; p = 0.002) were independently associated with RRT (Table 2).