There were significant differences between men and women in terms of BMI; eGFR; and serum creatinine, uric acid, triglyceride, and HDL-C levels; use of drugs, including antihypertensive agents, angiotensin receptor blockers, angiotensin-converting enzyme inhibitors, and antihyperuricemic agents; and the presence of hypertension, hyperuricemia, and hypertriglyceridemia. The gene discussed is ACE; the disease is hypertensive disorder.