PKD1 and hyperuricemia: The univariate analyses showed that age (HR, 1.04; 95% CI, 1.01–1.08; p = 0.02); PKD1 mutation (HR, 3.61; 95% CI, 1.02-22.96, p < 0.05); eGFR (1 mL/min/1.73m2 increase) (HR, 0.83; 95% CI, 0.76-0.89; p < 0.001); urinary protein excretion (HR, 1.69; 95% CI, 1.17–2.39; p = 0.01); hyperuricemia (HR, 3.09; 95% CI, 1.23–8.75; p = 0.02); and serum phosphate level (HR, 4.61; 95% CI, 2.14–10.27; p < 0.001) were significant risk factors associated with RRT.