To obtain a fuller understanding of the role of A7 and A8 in plaque formation, BT or EBL cells were infected with C500 (WT), A7STOP-207, A8STOP, A7STOP-207A8STOP or WC11 and immunostained with a monoclonal antibody against the viral gp115 complex at day 4 post-infection (Fig 4) [45]. This evidence concerns the gene EMILIN1 and infection.