KPNA2 was identified as a potential biomarker for non-small-cell lung cancer (NSCLC) by integration of the cancer cell secretome and tissue transcriptome.[53] Xiaolei's study provided direct evidence to demonstrates that KPNA2 may contribute to nuclear translocation in lung cancer.[54] So far, we have not found any research and reports on the GPR137C gene, which may become an innovation and hot spot for future research. This evidence concerns the gene KPNA2 and lung carcinoma.