In addition, H2AFX had significant co-expression patterns with markers of T cells CD4 memory CCR7 (P = 0.046), IL7R (P < 0.001) and macrophage M0 markers CD163 (P = 0.037), CD14 (P = 0.020), ITGAM (P = 0.043) and MRC1 (P = 0.038) in ACC (Supplementary Figure S5B–G). Here, H2AX is linked to adrenal cortex carcinoma.