But the severity of B. melitensis 16M infection in the Flu-BA_Omp19-SOD–vaccinated sheep and goats during the entire period (for up to 6 months PLV) of observation revealed the infection index (Figure 3A: 3.2 ± 0.9–6.0 ± 0.8; P = 0.001–P < 0.0001) and Brucella colonization in lymph nodes and organs (Figure 3B: 0.1 ± 0.1–2.0 ± 0.5 log10 CFU/g of tissue; P = 0.04–P < 0.0001) were significantly lower than those in the control group (infection index 9.8 ± 0.6–11.8 ± 0.5; Brucella colonization 0.1 ± 0.1–3.3 ± 0.2 log10 CFU/g of tissue). Here, SOD1 is linked to infection.