MUC16 and ovarian cancer: For example, MUC16, also known as CA125, is a widely used biomarker for the diagnosis of ovarian cancer (Yonezawa et al., 2011; Jonckheere and Van Seuningen, 2018) and was also found to be over-expressed in several other human malignancies, including pancreas, breast, and lung (Aithal et al., 2018).