ERBB2 and gastric cancer: Adjuvant or neoadjuvant therapy combined with surgery is commonly used to treat advanced GC, while targeted drugs for advanced GC, such as the HER2 (also known as ERBB2) antibody trastuzumab, and the VEGFR-2 antibody ramucirumab, are still in clinical trials (Van Cutsem et al., 2016).