NLRP3 and diabetes mellitus: Diabetic nephropathy is characterized by typical aseptic inflammation, and the role of inflammasomes in diabetes has also been discovered, as NLRP3 activation was found in diabetic patients as well as podocytes and endothelial cell injury (Boini et al., 2014; Chen et al., 2015; Shahzad et al., 2015; Koka et al., 2019).