ITGAM and Dravet syndrome: However, we reported a significant decrease in neutrophil CD11b at baseline in children with DS (n = 23, mean age 8.67 years) compared to controls (n = 21, age 7.4 years), and a significantly greater rise in CD11b post lipopolysaccharide (LPS; endotoxin) stimulation in the DS cohort vs. controls (43).