Both pro and anti-inflammatory mediators were elevated in in a murine model of sepsis with early deaths and high Interleukin- 6, Tumor necrosis factor α (TNF-α), Macrophage inflammatory protein 2 (MIP-2), Interleukin 1 receptor antagonist (IL-1ra) predicted mortality within 24 h (92). The gene discussed is TNF; the disease is Sepsis.