PIK3CA and ovarian cancer: The results demonstrated that the top mutations in ovarian cancer overall are TP53 (p53), FOXL2 (Forkhead box protein L2), KRAS (Kirsten Ras oncogene homolog), PIK3CA (Phosphatidylinositol 4,5-bispohsphate 3-kinase catalytic subunit alpha), ARID1A (AT-rich interaction domain 1A), and BRAF (B-Raf proto-oncogene) (Table 1).