FGS1 and LS are two allelic XLID syndromes, with mutations in the MED12 gene, that share some overlapping clinical features, such as dysgenesis of the corpus callosum, macrocephaly, hypotonia, intellectual disability, and behavioral disturbances (Risheg et al., 2007; Schwartz et al., 2007). Here, LIAS is linked to Intellectual disability.