FITM1 and hepatocellular carcinoma: Though the exploration of FITM1 in silico strongly indicated that FITM1 hypermethylation participated in the progression of non-viral HCC by silencing FITM1 expression and it could act as a tumor suppressor gene, related experiments of FITM1 expression, and FITM1 methylation in non-viral HCC still need to be conducted in vitro and in vivo in the continued study.