MALAT1 and neoplasm: Genetic loss or treatment with antisense oligonucleotides targeting MALAT1 results in alterations in the expression and splicing patterns of genes important for breast cancer cell differentiation, migration and oncogenesis; and results in tumor cell differentiation, slower tumor growth, and less metastasis in the MMTV-PyMT model of mouse mammary carcinoma (Arun et al., 2016).