In human colorectal cancer cells, MALAT1 expression is up-regulated by YAP1 (Sun et al., 2019), sponges miR-126-5p and miR-20b-5p, and thereby up-regulates the expression of tumor cell stemness proteins such as Oct4 and Nanog and metastasis-associated molecules such as VEGF, SNAI2, and TWIST (Sun et al., 2019; Tang et al., 2019). Here, POU5F1 is linked to colorectal cancer.