MALAT1 and colorectal cancer: By analyzing seven independent human colorectal cancer tissue gene expression-patient prognosis datasets, Kwok et al. have found that MALAT1 gene expression positively correlates with the expression of the tumor suppressor PTEN, and that decreased expression levels of MALAT1 and PTEN are significantly associated with increased mortality in colorectal cancer patients (Kwok et al., 2018).