MALAT1 binds miR-1, miR-124, and miR-448, and acts as a ceRNA to reduce CDC42 and up-regulate CDK4 expression, leading to breast cancer cell cycle progression, cell migration, and invasion (Chou et al., 2016; Feng et al., 2016; Bamodu et al., 2016). Here, CDK4 is linked to breast cancer.