KIF1A is responsible for the transport of membranous organelles and synaptic vesicles in neurons, and mutations in KIF1A have been associated with hereditary spastic paraplegia (HSP), hereditary sensory and autonomic neuropathy type 2 (HSANII), and intellectual disability (Riviere et al., 2011; Citterio et al., 2015). Here, KIF1A is linked to hereditary spastic paraplegia.