GAS6 and neoplasm: To determine which cell types produce Gas6 in pancreatic tumors, tumors were harvested at day 23, and tumor cells (CD45–/zsGreen+), non-immune stromal cells (CD45–/zsGreen–), M1-like macrophages (CD45+/F4/80+/CD206–) and M2-like macrophages (CD45+/F4/80+/CD206+) were isolated by flow cytometry (Figure 2A, Supplementary Figure 2A) and analyzed for the expression of gas6 (Figures 2A,B).