Changes in mRNA and protein levels of nucleolin, aquaporin 4, and connexin 43 (markers involved in ribosomal RNA transcription, potentially viral replication, water transport, and changes in brains of subjects with autism): nucleolin mRNA and aquaporin 4 significantly decreased in neocortex at P0 and P35. Protein levels were significantly upregulated at P35 and P56 in neocortex and P56 in cerebellumMicrocephalin mRNA was significantly decreased in neocortex at P56 and protein levels were significantly decreased at P56 in the cerebellum. The gene discussed is NUCLEOLIN; the disease is autism.