NFKB1 and monocytic leukemia: IGU can inhibit nuclear factor-kappa B (NF-κB) activation by interfering with NF-κB translocation from the cytoplasm to the nucleus without affecting the degradation of Ikappa Balpa in lipopolysaccharide-stimulated THP-1 cells (human monocytic leukemia cell line) (Aikawa et al., 2002).