To explore the molecular mechanism underlying the effects of axl-148b chimeric molecules on metastatic traits, we evaluated the expression of ALCAM and ITGA5, two miR-148b-3p direct targets based on TargetScan 6.2 (http://www.targetscan.org/) and miRDB (http://mirdb.org/index.html) prediction algorithms, able to coordinate tumor cell extravasation 7, 8. This evidence concerns the gene ALCAM and neoplasm.