We, therefore, treated 4175-TGL and SKBR3 breast cancer, MA-2 melanoma or A549 lung cancer cells, with GL21.T, axl-148b or scr-148b molecules and evaluated ALCAM and ITGA5 protein expression levels compared to cells transfected with miR-148b precursors (pre-148b) or controls (pre-ctrl). The gene discussed is ITGA5; the disease is breast cancer.