The MicroRNA-139-5p inhibits cell proliferation and invasion by targeting RHO-associated coiled-Coil-Containing Protein Kinase 2 in Ovarian Cancer 33, which acts as a tumor suppressor by targeting ELTD1 and regulating the cell cycle in glioblastoma multiforme 31, affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition 32, regulates proliferation of hematopoietic progenitors, and is repressed during BCR-ABL-mediated leukemogenesis 32, and controls translation in myeloid leukemia through EIF4G2 40. Here, ROCK2 is linked to neoplasm.