Therefore, we further assessed the mRNA expression of the coding gene SLC2A1 (GLUT1), which is on the opposite strand of SLC2A1‐AS1. As expected, the mRNA expression of the oncogene SLC2A1 was dramatically upregulated in HCC samples (Figs 1E and S2A) as well as in HCC cell lines (Fig. S2B). This evidence concerns the gene PTGDR and hepatocellular carcinoma.