DVL1 and Robinow syndrome: Robinow syndrome is a rare heterogeneous heritable disorders caused by mutations in genes, for example, WNT5A (MIM 164975), ROR2 (MIM 602337), FZ2 (MIM 258315), DVL (DVL1; MIM 601365, DVL3; MIM: 601368), and NXN (MIM 612895).7 These genes encode for components of the Wnt signaling, which controls convergent extension: a polarized cell migration that narrows and extends the body axis during vertebrate gastrulation as well as limb development and skeletal morphogenesis and regulates cell polarity, motility, survival, proliferation, and differentiation.8, , -11