AHRR and post-traumatic stress disorder: Ten loci achieved genome-wide significance, the most significant of which, cg05575921 (p = 4.27 × 10-11, FDR = 2.15 × 10-5), was located in the smoking-associated gene AHRR. Many of the EWASs of PTSD have also used Gene Set Enrichment Analysis or Functional Network Analysis of genome-wide DNAm as a follow up to their genome-wide association analyses.